![]() ![]() Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Metformin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin helps to control the amount of glucose (sugar) in your blood. Metformin is in a class of drugs called biguanides. Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Talk to your doctor about the risk(s) of taking metformin. Your doctor will order certain tests before and during treatment to check how well your kidneys are working and your body's response to metformin. Keep all appointments with your doctor and the laboratory. Ask your doctor how much alcohol is safe to drink while you are taking metformin. Drinking alcohol increases your risk of developing lactic acidosis or may cause a decrease in blood sugar. Tell your doctor if you regularly drink alcohol or sometimes drink large amounts of alcohol in a short time (binge drinking). If you experience any of the following symptoms, stop taking metformin and call your doctor immediately: extreme tiredness, weakness, or discomfort nausea vomiting stomach pain decreased appetite deep and rapid breathing or shortness of breath dizziness lightheadedness fast or slow heartbeat flushing of the skin muscle pain or feeling cold, especially in your hands or feet. Your doctor will tell you exactly when you should stop taking metformin and when you should start taking it again. You may need to stop taking metformin before the procedure and wait 48 hours to restart treatment. Also, tell your doctor if you plan to have any x-ray procedure in which dye is injected, especially if you drink or have ever drunk large amounts of alcohol or have or have had liver disease or heart failure. If you are having surgery, including dental surgery, or any major medical procedure, tell the doctor that you are taking metformin. You may have to stop taking metformin until you recover. Tell your doctor if you have recently had any of the following conditions, or if you develop them during treatment: serious infection severe diarrhea, vomiting, or fever or if you drink much less fluid than usual for any reason. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Keveyis), methazolamide, topiramate (Topamax, in Qsymia), or zonisamide (Zonegran). Taking certain other medications with metformin may increase the risk of lactic acidosis. Also, tell your doctor if you are over 65 years old and if you have ever had a heart attack stroke diabetic ketoacidosis (blood sugar that is high enough to cause severe symptoms and requires emergency medical treatment) a coma or heart or liver disease. Your doctor will probably tell you not to take metformin. Tell your doctor if you have kidney disease. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Metformin may rarely cause a serious, life-threatening condition called lactic acidosis. Portions of this document last updated: July 01, 2023Ĭopyright: © Merative US L.P. You may report side effects to the FDA at 1-80. If you notice any other effects, check with your healthcare professional.Ĭall your doctor for medical advice about side effects. Other side effects not listed may also occur in some patients. Redness or other discoloration of the skin Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. ![]() Some side effects may occur that usually do not need medical attention. Get emergency help immediately if any of the following symptoms of overdose occur: Symptoms of overdose Sores, ulcers, or white spots on the lips or in the mouth Red skin lesions, often with a purple center Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongueīlistering, peeling, or loosening of the skin Check with your doctor immediately if any of the following side effects occur: Rare ![]()
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